Notio Nova : A New Idea

Notio Nova: A New Idea by George P. Sakalosky, Ph.D. Here is a new and unique idea that describes both the driving force behind cancer and its potential cure. In this book, quantum concept and model developed by the author will take you into a territory completely off the commonly accepted research track for understanding carcinogenesis. Notio Nova rejects the common view that mutations in DNA produce both a cancer genome and a potential cure; instead, it suggests that the development of the cancer genome begins in DNA with the production of a chemical bond lesion-an ozonide-located inside a promoter TATA box in the Replication Origin of the Genome. The lesion locks the TATA box switch ON and causes the well known unregulated replication of the cancer genome that sustains itself via various mutations. This is the conclusion of a fifty-two year study using a new technique in molecular modeling which brought forth the design, synthesis, and successful testing of three lesion-destroying, anticancer analogue compounds. The conclusion of this new, unique research suggests that the old idea of mutation has failed to produce a cure, so a new idea must come forth and is here presented.